FIGURE 1.

Patient selection. B, benign; LB, likely benign; LP, likely pathogenic; MEP, multigene epilepsy panel; P, pathogenic; VUS, variant(s) of uncertain significance. (a) Eligible cases included patients meeting the following criteria: pediatric patient (1–17 years), clinically confirmed epilepsy, unknown etiology for epilepsy prior to MEP testing, received genetic testing with a MEP and actively followed for at least 1 year after epilepsy diagnosis with medical records documented in the electronic medical record since presentation. (b) Molecular diagnosis was defined as either a single pathogenic variant (P) or likely pathogenic variant (LP) in a gene associated with autosomal dominant (AD), X‐linked, or two P/LP variants (or a single homozygous variant) in genes associated with autosomal recessive (AR) inheritance.