Table 3.

Treatment-emergent adverse events.

Safety event	S48168 (ARM210) dose group
	120 mg/day (N = 3)		200 mg/day (N = 4)
	Events	Participants	Events	Participants
	N	N	N	N
Total treatment-emergent adverse events	17	3	9	3
Treatment-emergent adverse events ≥ grade two in severitya	2	2	1	1
Treatment-emergent adverse events at least possibly related to S48168 (ARM210)	2	2	0	0
Adverse events of special interest	0	0	0	0
Serious adverse events	0	0	0	0
Deaths	0	0	0	0

^aDefined per NCI Common Terminology Criteria for Adverse Events (version 5.0).