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. 2023 Aug 26;65(2):100434. doi: 10.1016/j.jlr.2023.100434

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© 2023 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 3 — Time-dependent changes in serum and liver lipids after CL-316,243 administration. A: Time-dependent changes in serum cholesteryl ester (CE), triglyceride (TAG), and free fatty acids (FFA) after CL-316,243 administration. (time points 0, 0.5, 1, 2, 3, 5, 12 h). B: Cluster analysis of major lipid classes. (time points 0, 0.5, 1, 2, 3, 5, 12 h). C: Liver triglycerides, CE, lysophosphatidylethanolamine, and FFAs measured after saline or CL-316,243 administration. D: Dynamic changes in hepatic genes expression with activation of adipose tissue lipolysis. Tissues were collected a designated times after a single dose of CL treatment. (n = 4, ∗: P < 0.05, ∗∗: P < 0.01, ∗∗∗: P < 0.005).