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. 2023 Aug 26;65(2):100434. doi: 10.1016/j.jlr.2023.100434

Fig. 5.

Fig. 5

Dietary palmitate and linoleate utilization in response to activation of lipolysis. A: Percentage of 13CO2 release after gavage with 13C-palmitate. B: Percentage of 12CO2 release after gavage with 13C-palmitate. C: Percentage of 13CO2 release after gavage with 13C-linoleic acid. D: Percentage of 12CO2 release after gavage with 13C-linoleic acid. E and F: Area under the Curve (AUC) of Energy Expenditure (EE) (E) or oxygen consumption (F) after saline or CL treatment in mice given 13C-palmitate or 13C-linoleic acid. G: 13C-CO2 production corrected by fractional labeling of serum 13C-palmitate or 13C-linoleate. Mice were gavaged with U-C13 palmitic acid or U-C13 linoleic acid, followed by intraperitoneal injection an hour later with saline or CL-316,243. Exhaled 13CO2 for each cage was normalized to total CO2 abundance to quantify changes in systemic palmitic acid or linoleic acid utilization. ∗∗: P < 0.01, ∗∗∗∗: P < 0.001.