Table 1.
Baseline Characteristics, Overall and by eGFR Category
| Characteristic | Overall (N = 562) |
eGFR ≥60 mL/min/1.73 m2 (N = 145) | eGFR 45-<60 mL/min/1.73 m2 (N = 96) | eGFR 30-<45 mL/min/1.73 m2 (N = 191) | eGFR 15-<30 mL/min/1.73 m2 (N = 106) | eGFR <15 mL/min/1.73 m2 (N = 24) |
|---|---|---|---|---|---|---|
| SPPB, mean (SD) | 9.5 (2.5) | 10.2 (2.3) | 9.2 (2.8) | 9.5 (2.5) | 9.0 (2.6) | 9.0 (2.7) |
| Gait speed (m/s), mean (SD) | 0.95 (0.27) | 1.02 (0.25) | 0.94 (0.29) | 0.93 (0.26) | 0.91 (0.27) | 0.98 (0.25) |
| eGFR (mL/min/1.73 m2), mean (SD) | 48.1 (24.3) | 83.5 (12.9) | 51.6 (4.2) | 37.6 (4.1) | 23.6 (4.2) | 11.9 (2.7) |
| UACR (mg/g), mean (SD) | 367.0 (947.9) | 41.8 (162.0) | 151.4 (571.0) | 299.0 (667.6) | 826.7 (1282.7) | 1703.4 (2339.6) |
| Age (years) mean (SD) | 69.3 (9.8) | 67.9 (9.8) | 70.5 (9.2) | 70.4 (9.6) | 69.7 (9.5) | 61.9 (10.6) |
| Female sex, N (%) | 280 (49.8) | 82 (56.6) | 48 (50.0) | 101 (52.9) | 44 (41.5) | 5 (20.8) |
| Race, N (%) | ||||||
| White | 449 (79.9) | 117 (80.7) | 78 (81.3) | 161 (84.3) | 80 (75.5) | 13 (54.2) |
| Black | 86 (15.3) | 20 (13.8) | 12 (12.5) | 21 (11.0) | 23 (21.7) | 10 (41.7) |
| Other | 27 (4.8) | 8 (5.5) | 6 (6.3) | 9 (4.7) | 3 (2.8) | 1 (4.2) |
| Education (years), mean (SD) | 14.3 (2.7) | 15.1 (2.6) | 14.4 (3.0) | 14.3 (2.6) | 13.5 (2.6) | 13.1 (2.5) |
| BMI (kg/m2), mean (SD) | 31.4 (7.2) | 29.6 (6.9) | 32.4 (7.8) | 32.1 (7.3) | 31.5 (6.4) | 31.2 (8.9) |
| DM, N (%) | 274 (48.8) | 61 (42.1) | 46 (47.9) | 90 (47.1) | 63 (59.4) | 14 (58.3) |
| Moderate to severe CI, N (%) | 159 (28.3) | 37 (25.5) | 22 (22.9) | 47 (24.6) | 41 (38.7) | 12 (50.0) |
| CHF, N (%) | 79 (14.1) | 7 (4.8) | 15 (15.6) | 34 (17.8) | 18 (17.0) | 5 (20.8) |
| Hemoglobin (g/dL), mean (SD) | 13.0 (1.7) | 13.8 (1.2) | 13.3 (1.3) | 12.9 (1.6) | 12.0 (1.9) | 11.3 (1.7) |
| Systolic BP (mm Hg), mean (SD) | 132 (18.5) | 129 (17.3) | 130 (14.6) | 133 (17.9) | 136 (19.8) | 142 (28.8) |
Abbreviations: BMI, body mass index; BP, blood pressure; CHF, congestive heart failure; CI, cognitive impairment; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate using creatinine; SD, standard deviation; SPPB, short physical performance battery; UACR, urine albumin to creatinine ratio.