TABLE 2.
Bactericidal antibody activity of guinea pig anti-rLbpB antibodies
| Strain | Localea | Sourceb | LbpB size (kDa) | Bactericidal antibody activityc |
|---|---|---|---|---|
| 4223 | New York | MEF | 105 | ++ |
| Q8 | Quebec, Canada | Sputum | 105 | ± |
| VH19 | Texas | MEF | 105 | + |
| LES-1 | Finland | MEF | 102 | − |
| H-04 | Nova Scotia | MEF | 100 | + |
| 3 | New York | Sputum | 100 | ++ |
a
Geographic locale where strain was isolated.
b
Anatomical source of clinical isolate. MEF, middle ear fluid from otitis media patient.
c
Killing by anti-4223 rLbpB antiserum diluted 1:64, compared to negative controls: −, 0 to 25% killing; ±, 26 to 49% killing; +, 50 to 75% killing; ++, 76 to 100% killing.