Zhao 2021.
Study characteristics | |
Methods | Unblinded RCT |
Participants | Outpatients with confirmed recurrent COVID‐19 (mild), isolated and treated at 5 centres in China |
Interventions | Favipiravir, standard of care |
Outcomes | Time to achieve two consecutive (at intervals of more than 24 hours) negative RT‐PCR result for SARS‐CoV‐2 RNA in nasopharyngeal swab and sputum sample; changes in routine blood test and CRP (C‐reactive protein); count and proportion of T lymphocyte subsets in peripheral blood and changes in cytokines; relationship between the antibody titre and the SARS‐CoV‐2 RNA re‐negative time; adverse events. |
Notes |
COVID‐19: coronavirus disease 2019; CT: computed tomography; ICU: intensive care unit; NEWS(2): National Early Warning Score (2); PaO2/FiO2: arterial oxygen partial pressure/fractional inspired oxygen; PCR: polymerase chain reaction; RCT: randomized controlled trial; RT‐PCR: reverse transcriptase polymerase chain reaction; SARS‐CoV‐2: severe acute respiratory syndrome coronavirus 2; SOC: standard of care; SpO2: blood oxygen saturation