Figure 3.

Imbalanced (imbal) contact matrices bias the impact of age-specific severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination strategies. Percent difference in cumulative infections averted in models parameterized with imbalanced versus balanced (bal) contact matrices when 50% of the population aged <15 years was vaccinated, using examples of different age-demographic settings: Gambia (A), Luxembourg (B), and Singapore (C). Percent difference in cumulative infections averted in models parameterized with imbalanced versus balanced contact matrices when 50% of the population ≥15 was vaccinated, using examples of different age-demographic settings: Gambia (D), Luxembourg (E), and Singapore (F). One infected individual was seeded per age group, per model. Cumulative infections averted were compared 1 year after seeding in a completely susceptible and closed population, in the absence of additional public health interventions other than vaccination. Contact matrices from Prem et al. (8, 9).