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. 2024 Feb 5;16:22. doi: 10.1186/s13073-024-01298-4

Table 3.

Overlap of commonly identified individuals using different PRS estimators

Thresholds PRS-16 vs. PRS-16-CV (n,%) PRS-16 vs. PRS-Bayes (n,%) PRS-16-CV vs. PRS-Bayes (n,%)
> 60th 10,865 (90) 5998 (50) 6068 (50)
> 70th 7942 (88) 3690 (41) 3726 (41)
> 80th 5161 (85) 1892 (31) 1905 (32)
> 90th 2470 (82) 583 (19) 573 (19)
> 95th 1218 (78) 174 (12) 163 (11)

The number and percentage of individuals that can be commonly identified with the same PRS-based risk groups by any of the two PRS estimators (PRS-16 vs. PRS-16-CV; PRS-16 vs. PRS-Bayes; PRS-16-CV vs. PRS-Bayes) were shown as the threshold of PRS risk increases