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. 2024 Feb 5;12:20. doi: 10.1186/s40168-023-01734-4

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Metagenomic analysis of gut microbiota in M-CON and M-PEDV piglets. A Gene number distribution of M-CON pig and M-PEDV pig gut microbes (n=8/group). B Analysis of significantly upregulated (top 4) and downregulated (top 4) species in the abundance table. C Species comparison analysis (top 10). D LEfSe analysis (LDA score > 4). Functional annotation and abundance information of the samples in the KEGG (E) and eggNOG (G) databases and clustering at the level of functional differences. F Functional annotation and statistics of samples in the CAZy database. The results are presented as the means ± SD, and statistical significance was calculated by one-way ANOVA. ****P < 0.0001