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. 2023 Oct 30;33(4):333–341. doi: 10.1093/hmg/ddad185

Figure 2.

Figure 2

The effects of altered expression of miR-1307-5p and miR-192-3p on the proliferation of SW480 and HCT-116 cells. (A) qRT-PCR assays to detect miR-1307-5p expression in transfected cells with miR-1307-5p mimics and miR-1307-5p inhibitor in the HCT116 cell line. (B) qRT-PCR assays to detect miR-192-3p expression in transfected cells with miR-192-3p mimics and miR-1307-5p inhibitor in SW480 and HCT-116 cell lines. (C) CCK-8 assays to examine the proliferation of HCT116 cells transfected with mimics of either miR-1307-5p or miR-192-3p and inhibitors of either miR-1307-5p or miR-192-3p. (D) CCK-8 assays to examine the proliferation of SW480 cells transfected with either miR-192-3p mimic or miR-192-3p inhibitor. (E) and (F) Colony-formation assay was performed to evaluate the proliferation of HCT116 cells after overexpressing either miR-1307-5p or miR-192-3p and silencing either miR-1307-5p or miR-192-3p. Colony-formation assay was performed to evaluate the proliferation of SW480 cells after overexpressing miR-192-3p and silencing miR-192-3p. Data are presented as mean ± SD; * and #P < 0.05, ** and ##P < 0.01, *** and ###P < 0.001, no significant (NS).