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F-DPC/pIL-12/iPDL-1 treatment increased the expression of IL-12, IFN-γ and TNF-α in vivo. Tumor tissues, ascites and serums were collected after different treatments with GS, F-DPC (vehicle), F-DPC/pvax, iPDL-1, F-DPC/pIL-12, DPC/pIL-12/iPDL-1 and F-DPC/pIL-12/iPDL-1, and the expressions of IL-12 (A), IFN-γ (B) and TNF-α (C) in tumor tissues, ascites and serums were detected by ELISA. Data are presented as mean ± SEM (n = 3). ∗∗P < 0.01, ∗∗∗P < 0.001, ∗∗∗∗P < 0.0001).
