Table 3.
Flow Cytometric Parameters Prior to LVAD Implantation in Patients Suffering from Infection Within the First 3 Months Following LVAD Implantation and Infection-Free Patients
| Infection Group (n = 23) | Non-Infection Group (n = 31) | p value | |
|---|---|---|---|
| Total DCs [%] | 0.47 ± 0.36 | 0.56 ± 0.27 | 0.15 |
| BDCA1+ DCs [%] | 41.8 ± 14.5 | 43.5 ± 13.4 | 0.34 |
| BDCA2+ DCs [%] | 25.0 ± 10.5 | 31.2 ± 12.4 | 0.03 |
| BDCA3+ DCs [%] | 62.1 ± 20.4 | 64.9 ± 25.2 | 0.33 |
| BDCA4+ DCs [%] | 23.7 ± 10.6 | 28.7 ± 10.8 | 0.05 |
| Tregs [%] | 7.6 ± 3.4 | 6.7 ± 2.3 | 0.17 |
| CD19+ B cells [%] | 4.9 ± 3.2 | 8.6 ± 5.1 | < 0.01 |
| CD3+ T cells [%] | 39.2 ± 21.4 | 49.6 ± 13.9 | 0.03 |
| CD3+/CD8+ T cells [%] | 27.1 ± 9.8 | 29.7 ± 14.3 | 0.23 |
| CD8+/CD57+ T cells [%] | 38.1 ± 19.0 | 30.6 ± 14.4 | 0.06 |
| CD8+/CD25+ T cells [%] | 6.8 ± 7.2 | 5.5 ± 4.5 | 0.23 |
| CD3+/CD4+ T cells [%] | 67.6 ± 11.2 | 64.3 ± 16.0 | 0.21 |
| CD4+/CD57+ T cells [%] | 13.2 ± 14.6 | 8.6 ± 9.3 | 0.10 |
| CD4+/CD25+ T cells [%] | 18.1 ± 16.8 | 14.6 ± 16.0 | 0.22 |
| Total NK cells [%] | 9.9 ± 5.8 | 9.1 ± 7.5 | 0.36 |
| CD57+ NK cells [%] | 32.5 ± 16.4 | 28.5 ± 16.2 | 0.19 |
| CD56bright NK cells [%] | 4.8 ± 3.1 | 6.2 ± 5.0 | 0.13 |
| CD56dim NK cells [%] | 56.2 ± 25.1 | 58.0 ± 15.6 | 0.39 |
| CD56neg NK cells [%] | 33.0 ± 24.5 | 30.6 ± 12.4 | 0.34 |
| CD56dim/neg NK cells [%] | 89.2 ± 7.5 | 88.5 ± 7.5 | 0.38 |
Abbreviations: BDCA1/2/3/4, blood dendritic cell antigen 1/2/3/4; CD, cluster of differentiation; DCs, dendritic cells; NK cells, natural killer cells; Tregs, regulatory T cells.