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. 2024 Jan 22;14:1273170. doi: 10.3389/fendo.2023.1273170

Table 1.

Comparison of clinical data at the time of initial diagnosis in three groups of children.

Variable RP-CPP SP-CPP PT
Age[M(P25, P75), years] 8.0 (7.5,8.0)ab 7.0 (6.5,7.5) 7.0 (6.0,7.0)
Height[(x̅ ± s), cm] 135.8 ± 6.4ab 128.4 ± 6.5 125.9 ± 7.4
TH[(x̅ ± s), cm] 159.8 ± 3.9 161.7 ± 3.2 161.2 ± 3.8
PAH[(x̅ ± s), cm] 158.2 ± 6.3ab 164.7 ± 8.8 163.7 ± 7.6
Weight[M(P25, P75), kg] 33.0(29.0,38.2)ab 26.3(23.2,30.2) 24.0(22.05,27.4)
BMI[M(P25, P75), kg/m2] 17.6(16.3,19.8)ab 15.9(14.9,17.2) 15.3(14.4,16.8)
BA[M(P25, P75), years] 11.0(10.0,11.0)ab 9.0 (7.0,9.0) 8.0 (7.0,9.0)
BA-CA[M(P25, P75), years] 3.0 (2.0,3.0)ab 1.5 (0.1,2.0) 1.5 (0.3,2.0)
Baseline LH value [M(P25, P75),IU/L] 1.22(0.60,2.45)ab 0.69(0.25,1.13)a 0.20(0.20,0.50)
LH peak value [M(P25, P75), IU/L] 17.26(11.24,25.52)ab 9.31(6.52,11.89)a 3.22(2.85.3.97)
Baseline FSH value [M(P25, P75), IU/L] 4.21(2.67,6.10)a 3.63(2.54,5.70) 3.00(2.35,4.32)
FSH peak value [M(P25, P75), IU/L] 17.72(13.28,20.35) 17.50(15.03,21.55) 18.3(15.8,23.16)
LH peak value/FSH peak value [M(P25, P75)] 0.99(0.63,1.53)ab 0.53(0.37,0.71)a 0.18(0.14,0.23)
E2[M(P25, P75),pg/ml] 20.56(15.00,40.36)a 16.35(15.00,24.74)a 15.00(15.00,15.00)
testosterone [M(P25, P75),ng/dl] 18.50(11.19,24,72)ab 10.00(10.00,14.24) 10.00(10.00,12.79)
SHBG[M(P25, P75),nmol/L] 52.15(42.63,79.38)ab 70.15(51.33,98.23) 72.90(59.95,94.35)

TH for target height, PAH for predicted adult height, BMI for body mass index, BA for bone age, BA-CA for bone age minus chronological age, LH for luteinizing hormone, FSH for follicle-stimulating hormone, E2 for estradiol, SHBG for sex hormone-binding globulin.In the context of "a," the values were found to be statistically significant (P < 0.05) when compared with the PT group. Similarly, in relation to "b," the values also showed statistical significance (P < 0.05) when compared with the SP-CPP group.