Table 4.
General Clinical and Laboratory Parameter of All Subjects According to Serum Metrnl
| Variable | T1 | T2 | T3 | P |
|---|---|---|---|---|
| Serum Metrnl (pg/mL) | <233.65 | 233.65–346.24 | ≥346.24 | − |
| N | 117 | 118 | 117 | − |
| Percentage of MAFLD (%) | 67.52 | 66.95 | 15.38 | <0.001 |
| Sex(M/F) | 99/18 | 58/60 | 12/105 | <0.001 |
| #Age(years) | 40(32−55) | 46(33−58) | 41(32−51) | 0.103 |
| #BMI(kg/m2) | 26(24−27) | 25(23−27) | 23(21−24) | <0.001 |
| #WC(cm) | 91(86−98) | 89(84−95) | 82(74−88) | <0.001 |
| *HC (cm) | 101.76±6.36 | 100.10±5.81 | 98.71±7.27 | 0.003 |
| #SBP (mmHg) | 131(120−142) | 128(117−139) | 114(106−133) | <0.001 |
| #DBP (mmHg) | 84(78−90) | 83(78−88) | 75(71−85) | <0.001 |
| #FBG(mmol/L) | 5.23(4.87−5.89) | 5.25(4.88−5.59) | 4.92(4.58−5.23) | <0.001 |
| #TG(mmol/L) | 1.44(1.04−1.95) | 1.50(1.08−2.06) | 1.01(0.71−1.42) | <0.001 |
| *TC (mmol/L) | 5.11±0.87 | 5.09±1.02 | 4.68±0.83 | <0.001 |
| *LDL-C(mmol/L) | 3.17±0.67 | 3.24±0.79 | 2.94±0.63 | 0.003 |
| *HDL-C(mmol/L) | 1.27±0.29 | 1.27±0.28 | 1.35±0.25 | 0.027 |
| #UC(μmol/L) | 363.20(307.35−423.50) | 342.00(298.70−395.80) | 299.40(260.75−347.45) | <0.001 |
| #ALT(U/L) | 22.60(17.40−33.68) | 17.90(14.57−26.95) | 15.20(10.90−20.40) | <0.001 |
| #AST(U/L) | 23.10(20.10−27.80) | 22.40(19.70−26.70) | 20.50(18.00−24.60) | <0.001 |
| #γ-GGT(U/L) | 26.50(20.15−38.05) | 22.60(19.05−31.30) | 15.90 (13.30−22.65) | <0.001 |
| #Creatinine(μmol/L) | 77(65−83) | 67(59−80) | 59.30(51.90−68.10) | <0.001 |
| #WBC(×109/L) | 6.50(5.45−7.35) | 6.30(5.50−7.30) | 5.60(4.90−6.80) | 0.005 |
Notes: *Data normally distributed are shown as mean ± SD. One-way ANOVA test was performed. #Data with skewed distribution are shown as median (25th−75th). Kruskal–Wallis test was performed.
Abbreviations: BMI, body mass index; WC, waist circumference; HC, hip circumference; SBP, systolic blood pressure; DBP, diastolic blood pressure; FBG, fasting blood glucose; TG, Triglyceride; TC, Total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; UA, uric acid; ALT, alanine aminotransferase; AST, aspartate aminotransferase; γ-GGT, γ-gamma glutamyl transferase; WBC, white blood cell.