TABLE 4.
Significant associations of viral read count with AD in at least one ancestry group.
| African american | European ancestry | Caribbean hispanic | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean viral load | Mean viral load | Mean viral load | ||||||||||
| Virus | AD cases | Controls | Odds Ratio | p‐Value | AD cases | Controls | Odds ratio | p‐Value | AD cases | Controls | Odds ratio | p‐Value |
| Human alphaherpesvirus 1 (HSV‐1) * | 7.32 | 7.18 | 9.30 | 5.81 × 10‐3 | 6.04 | 5.26 | 4.95 | 2.27 × 10‐3 | 6.77 | 11.0 | 1.35 | 1.00 |
| Human Papilomavirus 71 (HPV‐71) * | 0.50 | 0.34 | 7.24 | 2.13 × 10‐4 | 0.05 | 0.07 | 0.04 | 0.06 | 0.05 | 0.02 | 0.70 | 1.00 |
| Torque teno virus 10 (TTV‐10) † | 0.05 | 0.01 | 5.34 × 102 | 0.01 | 0.003 | 0.003 | 0.56 | 1.00 | 0.01 | 0.01 | 3.04 | 1.00 |
*
Adjusted for 10 independent tests.
†
Adjusted for 59 independent tests.
Analyses were stratified by dataset (WES/WGS) and combined by meta‐analysis.