Skip to main content
. Author manuscript; available in PMC: 2024 Nov 14.
Published in final edited form as: Circulation. 2023 Sep 18;148(20):1582–1592. doi: 10.1161/CIRCULATIONAHA.123.066002

Figure 1. SNRK is increased in cardiac hypertrophy and its deletion leads to exaggerated hypertrophy.

Figure 1.

A, SNRK protein levels in heart tissue from mice subjected to sham or 4-weeks after TAC operation. B, Summary bar graph summary of Panel A (n=3 animals per condition, unpaired t-test, *P<0.05). C, Image of freshly extracted hearts from WT and cs-Snrk−/− mice 4-weeks after sham operation or TAC. Scale bar = 0.1 cm. D, HW/TL in WT and cs-Snrk−/− mice 4-weeks after sham operation or TAC (n>6 animals per condition, two-way ANOVA with Tukey’s test, *P<0.05). E-F, IVSd (E) and PWTd (F) in WT and cs-Snrk−/− mice 4-weeks after sham operation or TAC (n=6-10, two-way ANOVA with Tukey’s multiple comparisons test). G-H, EF (G) and FS (H) in WT and cs-Snrk−/− mice 3-weeks after sham operation or TAC (n=3-11, two-way ANOVA with Sidak’s multiple comparisons test, *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001.