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. Author manuscript; available in PMC: 2024 May 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2023 Nov 1;32(11):1599–1607. doi: 10.1158/1055-9965.EPI-23-0545

Table 2.

Summary of significant SNP-disease interactions for invasive melanoma (M-inv; top panel) and basal cell carcinoma (BCC; bottom panel).

Chr SNP Allele Odds Ratio P-value (FDR) Gene Location
16 rs9926296 A 0.809446 3.77E-12 FANCA intron 31
16 rs3743860 C 1.1965 1.29E-08 FANCA intron 31
16 rs2376883 A 0.848934 1.92E-06 FANCA intron 29
Chr SNP Allele Odds Ratio P-value (FDR) Gene Location

1 rs12046289 A 0.914388 0.000104 DCLRE1B intron 2
1 rs4149909 G 1.12746 0.021555 EXO1 exon 7
6 rs61748588 A 1.18706 0.049773 GTF2H4 exon 5
8 rs28928581 C 1.08347 0.043767 RRM2B intron 5
13 rs4942486 T 1.0483 0.011646 BRCA2 intron 21
14 rs4902628 C 0.958423 0.046463 RAD51B intron 11
16 rs9926296 A 0.920691 2.42E-09 FANCA intron 31
16 rs3743860 C 1.07056 5.88E-06 FANCA intron 31
16 rs2376883 A 0.939527 0.000104 FANCA intron 29
16 rs1800347 C 1.11993 0.004734 FANCA intron 33
16 rs62989960 T 0.874634 0.004734 FANCA intron 25

Odds ratios represent the probability of the tested minor allele of each SNP to be found in the disease versus healthy control group. Significance for each allele has been determined using the False Discovery Rate (FDR) method. Each SNP is annotated for its chromosomal position (Chr), the localizing gene, and its location (intron or exon) within the gene.