Figure 5. Tumor growth is attenuated upon aCx26-pep treatment in vivo.

A) Following palpability of tumors in the subcutaneous right flank generated by MDA-MB-231 cell injection, mice were intratumorally treated with 50 μl of either 0.1 mM peptide or vehicle (1% DMSO) every other day for 20 days and monitored by weekly IVIS imaging. B) Representative IVIS images of treated mice at Day 0 and Day 42. C) Tumors treated with aCx26-pep exhibited attenuated tumor growth over time compared to control groups. n=8 mice per group; * p<0.05, ** p<0.01, *** p<0.001 by two-way ANOVA.