Table 1.

List of TFs involved in regulating ABC transporter expression and their binding site in the proximal promoter region of MDR-linked ABC transporters

Transcriptional factor	ABC gene	Binding site in ABC gene promoter region	Gene expression pattern	Ref.
NF-κB	ABCB1	GGGAATTCTCCTTTCGGGG	Upregulation	(Chen et al., 2014)
AP-1	ABCB1	GCATTCAGTCAATCCG	Upregulation	(Chen et al., 2014)
ERRγ	ABCB1	TCAAGGTCA	Upregulation	(Chen et al., 2020)
NF-Y	ABCB1	CCAAT box	Upregulation	(Dolfini et al., 2016)
STAT3	ABCB1	TTCCACTAA	Upregulation	(Zhang et al., 2011)
Gli	ABCB1	GACCACCCA	Upregulation	(Chen et al., 2014)
CBF1	ABCC1	GTGGAGA	Upregulation	(Cho et al., 2011)
Androgen receptor (AR)	ABCG2	AAAGAAT	Upregulation	(Chung et al., 2019)
SMAR1	ABCG2	ATGCTGCA	Downregulation	(Xu et al., 2021)