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. 2024 Feb 1;16(1):2307586. doi: 10.1080/19490976.2024.2307586

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Figure 4. — A fungal signature differentiates ALD from NAFLD with significant fibrosis.

(a-b) Linear discriminant analysis (LDA) of (a) genera and (b) species of ALD F2-F4 vs NAFLD F2-F4. (c-d) Relative abundance of genera (c) Mucor and Debaryomyces, and of species (d) Malassezia restricta. (e) ROC curves of fungal genera and species for detecting ALD F2-F4 vs NAFLD F2-F4 (ALD F2-F4 patients, n = 10; NAFLD F2-F4 patients, n = 30). A p value of equal or less than 0.05 was considered as statistically significant. ALD, alcohol-associated liver disease; AUC, area under the curve; K, Kluyveromyces; M, Mucor; MR, Malassezia restricta; NAFLD, nonalcoholic fatty liver disease; ROC, receiver operating characteristic; SCO, Scopulariopsis/S. cordiae.