Table 2.
Detection rates and unadjusted risks and adjusted hazard ratios for post colonoscopy colorectal cancer (PCCRC) in patients with* and without# follow up event
| Sessile serrated lesion Detection Rate (SSLDR) (with at least 1 follow up event)* (n=26,901) | ||||||
|---|---|---|---|---|---|---|
| < 1.0 | 1.0 – < 2.0 | 2.0 – < 4.0 | 4.0 – < 6.0 | 6.0+ | ||
| Unadjusted risk PCCRC | % | 1.4% | 0.6% | 0.6% | 0.4% | 0.3%* |
| N | 58/4117 | 46/8075 | 22/3950 | 18/4011 | 18/6748 | |
| ***Adjusted Hazard | HR | 1.0 | 0.41 | 0.45 | 0.38 | 0.29 |
| 95% CI | Reference | 0.28–0.61 | 0.27–0.75 | 0.22–0.66 | 0.16–0.50 | |
| Sessile serrated lesion Detection Rate (SSLDR) (with/without follow up event)**(n= 114,197) | ||||||
| < 1.0 | 1.0 – < 2.0 | 2.0 – < 4.0 | 4.0 – < 6.0 | 6.0+ | ||
| Unadjusted risk PCCRC | % | 0.31% | 0.18% | 0.11% | 0.09% | 0.06%* |
| N | 58/18793 | 46/25824 | 22/19693 | 18/19518 | 18/30369 | |
| ***Adjusted Hazard | HR | 1.0 | 0.46 | 0.53 | 0.49 | 0.36 |
| 95% CI | Reference | 0.31–0.68 | 032–0.88 | 0.29–0.85 | 0.21–0.62 | |
p < 0.0001
Cox regression was used to model the hazard of PCCRC on SSLDR controlling for age, sex, presence of CSSPs, presence of advanced adenomas, year of index exam, indication of index exam, bowel prep quality, and having more than 1 surveillance exam.
Censored at 1st follow up or 6 months prior to last linkage date with the NH State Cancer Registry