The variables are sorted from left to right in descending order for the highest values in the Hyperinflammatory phenotype. Standardized values were calculated by assigning the mean of the variables as 0 and standard deviation as 1. All variables were collected on the day of study enrolment. Panel A: VALID cohort. Panel B: EARLI Cohort. BMI: body mass index, SBP: systolic blood pressure, ICAM-1: intercellular adhesion molecule-1, IL-6: interleukin 6, IL-8: interleukin 8, PAI-1: plasminogen activator inhibitor-1, sTNFR-1: soluble tumour necrosis factor receptor-1, WBC: white blood cell count, RR = Respiratory Rate, HR = Heart Rate.