Table 2.
Medication | Mechanism for Nephrotoxicity |
---|---|
ACEi and ARBs | Functional renal insufficiency (Hypotension) |
NSAIDS | Reduction in prostaglandin synthesis |
Antibiotics (Vancomycin, Aminoglycosides and Beta-lactams) | Acute tubular necrosis, acute interstitial nephritis, Crystal-induced acute kidney injury |
Intravenous contrast agents | Acute tubular necrosis |
Diuretics | Hypovolemia and hypotension |