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. Author manuscript; available in PMC: 2024 Feb 5.
Published in final edited form as: Sci Transl Med. 2024 Jan 17;16(730):eadf9735. doi: 10.1126/scitranslmed.adf9735

Table 2. Association between survival after symptom onset and TMEM106B rs3173615 status in FTLD-TDP.

β, regression coefficient; CI, confidence interval; min, minimum; max, maximum. β values, 95% CIs, and P values result from unadjusted linear regression models or linear regression models adjusted for age at death and sex. β values are interpreted as the difference in survival after symptom onset. P < 0.025 are considered statistically significant after correcting for multiple testing.

Unadjusted analysis Adjusted analyses

FTLD (N = 206) Median survival [years (min, max)] β (95% CI) P value β (95% CI) P value

CC/TT185 8 (2, 25) 0.00 (reference) NA 0.00 (reference) NA

CG/TS185 8 (1, 25) 0.523 (−0.802–1.847) 0.4373 0.725 (−0.539–1.989) 0.2594

GG/SS185 12 (3, 16) 3.036 (0.638–5.434) 0.0133 3.095 (0.781–5.409) 0.0090