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. Author manuscript; available in PMC: 2024 Nov 16.
Published in final edited form as: Mol Cell. 2023 Oct 5;83(22):3953–3971. doi: 10.1016/j.molcel.2023.09.016

Figure 2. Overview of the expanding field of tsRNA research.

Figure 2.

This illustration depicts the three main branches of current tsRNA research. These branches encompass the study of tsRNA biogenesis, which involves various tRNA modifications, RNases, and regulatory proteins. The molecular mechanisms of actions, and the roles of tsRNAs in both physiological functions and disease associations, is based on previous research and review articles10,11,15,82,214–218.