Table 2.
Baseline echocardiographic parameters
| Parameter | Wild type (N=20) | Bak−/− (N=22) | P value |
|---|---|---|---|
| LVEDV (μl) | 65.7±1.8 | 63.2±1.6 | 0.2901 |
| LVESV (μl) | 20.3±1.0 | 19.7±0.9 | 0.6253 |
| EF (%) | 66.7±1.8 | 67.5±1.5 | 0.7284 |
| IVS(d) (mm) | 1.01±0.047 | 0.94±0.019 | 0.2119 |
| IVS(s) (mm) | 1.40±0.095 | 1.40±0.046 | 0.9872 |
| PW(d) (mm) | 0.86±0.072 | 0.86±0.043 | 0.9703 |
| PW(s) (mm) | 1.24±0.082 | 1.23±0.079 | 0.9763 |
LVEDV – left ventricular end diastolic volume; LVESD – left ventricular end systolic volume; EF – ejection fraction; IVS(d) – thickness interventricular septum in diastole; IVS(s) – thickness interventricular septum in systole; PW(d)– thickness posterior wall in diastole; PW(s)– thickness posterior wall in systole. Data – mean ± SEM. Statistics – Student’s t-test. Note: Baseline echocardiographic data in this table is the same data listed under baseline in Figs. 7E and S5.