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. Author manuscript; available in PMC: 2024 Nov 13.
Published in final edited form as: Cancer Cell. 2023 Oct 19;41(11):1945–1962.e11. doi: 10.1016/j.ccell.2023.09.012

Figure 4. L. iners positive tumors have metabolic alterations compared to L. iners negative tumors.

Figure 4.

A. Principal coordinate analysis of relative abundances of tumor metabolites for L. iners+ (N=36) and L. iners− tumors (N=30). Dispersion Separability Criterion, p<0.005.

B. Volcano plot of differentially abundant metabolites. –Log10 (adj. p-value) threshold=1.0; log2 (Fold Change) threshold −1 to 1.

C. Supervised hierarchical clustering of differentially abundant metabolites.

D. Lollipop plot of pathway assignments for differentially enriched metabolites. Sorted by effect size on a log10 scale. * FDR-adj p<0.05.

Analyzed by HR-MS and IC-MS (A-D).