Table 3.
Mean cord blood MeHg of study population (N = 874) and associations of genotypes with Hg concentrations for the Nutrition Cohort 2 in the Seychelles Child Development Study. No p-value showed significance.
| SNP | Genotype | n | Cord MeHg (μg/L) | 95% CI | Gene p-value |
|---|---|---|---|---|---|
|
NFE2L2 rs2364723 |
GG | 485 | 33.84 | (32.01,35.68) | 0.678 |
| CG | 327 | 33.51 | (31.28,35.75) | ||
| CC | 62 | 36.02 | (30.89,41.15) | ||
|
NFE2L2 rs13001694 |
AA | 406 | 33.36 | (31.36,35.36) | 0.237 |
| AG | 382 | 35.02 | (32.95,37.08) | ||
| GG | 86 | 31.21 | (26.85,35.56) | ||
| KEAP1 rs8113472 | CC | 664 | 33.72 | (32.15,35.29) | 0.923 |
| CA | 190 | 34.30 | (31.37,37.23) | ||
| AA | 20 | 34.83 | (25.79,43.87) | ||
|
KEAP1 rs9676881 |
AA | 304 | 31.93 | (29.62,34.24) | 0.098 |
| AG | 409 | 35.28 | (33.29,37.28) | ||
| GG | 161 | 33.96 | (30.78,37.14) |