Table 1.

Summary of the most relevant LDL-C formulas

Formula	Equation	Reference
Friedewald’s	$\text{LDL}-\text{C}=\text{TC}-\text{HDL}-(\text{TG}/5)$	(3)
Extended Martin	$\text{LDL}-\text{C}=\text{TC}-\text{HDL}-(\text{TG}/“\text{Adjustable factor}”)$	(5)
Sampson-NIH	$\text{LDL}-\text{C}=\left(\text{TC}/0.948\right)-\left(\text{HDL}-\text{C}/0.971\right)-\left[\left(\text{TG}/8.56\right)+\left(\text{TG}\times \text{non}-\text{HDL}-\text{C}/2,140\right)-\left(\text{TG}\times \text{TG}/16,100\right)\right]-9.44$	(6)
Enhanced Sampson-NIH	$\text{eS}-\text{VLDL}-\text{C}=\left(\text{non}-\text{HDL}-\text{C}/3.81\right)-\left(\text{HDL}-\text{C}/8.93\right)+\left(\text{TG}/7.73\right)\text{+}\left[\left(\text{non}-\text{HDL}-\text{C}\times \text{TG}\right)/2050\right]-\left({\text{TG}}^2/13300\right)-\left(\text{ApoB}/2.49\right)-\left[\left(\text{ApoB}\times \text{TG}\right)/3550\right]+7.46.$	(10)