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. Author manuscript; available in PMC: 2024 Dec 1.
Published in final edited form as: Atherosclerosis. 2023 Nov 6;386:117364. doi: 10.1016/j.atherosclerosis.2023.117364

Table 6:

Comparison of lipid targets for all four formulas compared to LDL-C estimated using VLDL-C measured by ultracentrifugation in the FCHL dyslipidemia phenotype

Isolated Hypercholesterolemia
(n=38)
Mixed Dyslipidemia
(n=26)
Métric F-LDL-C M-LDL-C S-LDL-C eS-LDL-C F-LDL-C M-LDL-C eM-LDL-C S-LDL-C eS-LDL-C
LDL-C goal <100 mg/dL κ (95%CI) 0.78
(0.63-0.86)
0.78
(0.67-0.89)
0.81
(0.70-0.91)
0.80
(0.69-0.91)
0.65
(0.51-0.78)
0.63
(0.47-0.80)
0.63
(0.47-0.79)
0.78
(0.66-0.91)
0.83
(0.72-0.95)
AUC (95%CI) 0.99
(0.97-1)
0.99
(0.98-1)
0.99
(0.98-1)
0.99
(0.98-1)
0.96
(0.93-0.99)
0.95
(0.93-0.98)
0.96
(0.93-0.98)
0.97
(0.94-0.99)
0.96
(0.93-0.99)
LDL-C goal <70 mg/dL κ (95%CI) 0.80
(0.41-1.0)
0.56
(0.12-1)
0.80
(0.41-1)
1 (1-1) 0.22
(0.00-0.45)
0.49
(0.14-0.84)
0.34
(0.02-0.71)
0.36
(0.05-0.66)
0.59
(0.23-0.96)
AUC (95%CI) 0.99
(0.99-1)
1.00 (1-1) 1.00 (1-1) 1.00 (1-1) 0.94
(0.85-1)
0.91
(0.77-1)
0.92
(0.81-1)
0.94
(0.85-1)
0.95
(0.86-1)