Skip to main content
. Author manuscript; available in PMC: 2024 Nov 27.
Published in final edited form as: Mater Horiz. 2023 Nov 27;10(12):5500–5507. doi: 10.1039/d3mh01108a

Figure 3.

Figure 3.

Effects of polyplexes on methicillin-resistant S. aureus (MRSA) biofilm. a) Representative 3D views of confocal image stacks of red fluorescent protein (RFP)-expressing MRSA biofilm after 1 h incubation with Cy5.5-labelled polyplexes (Cyan). Overlay images show Cy5.5-polyplexes completely penetrate the entire biofilm, interacting with MRSA cells. Biofilm thickness is ~ 18μm. b) Screening the polymer and the polyplexes formulated with different N/P ratios via their antimicrobial activity against MRSA IDRL-6169 for biocompatibility.