Table 1.
Demographic information and descriptive statistics for PROGRESS subjects (n=437) in the study.
| N (%) | |
|---|---|
| Child Sex | |
| Male | 221 (50.57) |
| Female | 216 (49.43) |
| Socioeconomic Status at Pregnancy | |
| Lower | 228 (52.17) |
| Medium | 164 (37.53) |
| Higher | 45 (10.30) |
| Child Body Mass Index | |
| Normal | 241 (55.15) |
| Overweight | 104 (23.80) |
| Obese | 92 (21.05) |
| Indoor Tobacco Smoke Exposure at time of visit | |
| No | 394 (90.16) |
| Yes | 43 (9.84) |
| Season at 8-12 Year Visit | |
| Cold-dry | 107 (24.49) |
| Rainy | 289 (66.13) |
| Warm-dry | 41 (9.38) |
| Mean (Range) | |
| eGFR (mL/min/1.73 m2) | 99.61 (46.76-201.33) |
| Serum Cystatin C (mg/L) | 0.73.73 (0.32-1.56) |
| Urinary creatinine (mg/dL) | 102 (15.8-322) |
| Body mass index z-score | 0.86 (−3.00-3.98) |
| Age at urine collection (years) | 9.64 (8.08-11.87) |
| Average Seven-Day PM2.5 (μg/m3) | 18.79 (7.51-58.29) |
| Average 30-Day PM2.5 (μg/m3) | 18.83 (11.40-37.64) |
| Average Seven-Day Temperature (°C) | 16.26 (10.75-21.79) |
| Average 30-Day Temperature (°C) | 16.29 (10.99-21.29) |
| Urinary Kidney Injury Biomarkers at 8–12 years of age | Median (25th-75th percentile) |
| Albumin (mg/dl) | 22.71 (12.11-45.23) |
| Cystatin C (ng/mL) | 11.61 (4.61-21.57) |
| KIM-1 (ng/mL) | 0.44 (0.20-0.80) |
| NGAL (ng/mL) | 8.22 (3.36-23.08) |
| A1M (ng/mL) | 169.63 (106.55-263.62) |
| B2M (ng/mL) | 205.01 (75.49-455.99) |
| RBP4 (ng/mL) | 1372.85 (587.50-2682.94) |
| OPN (ng/mL) | 731.32 (236.23-1399.90) |
| Uromodulin (MFI) | 3837.98 (2390.00-5592.93) |
| GSTα (ng/mL) | 0.54 (0.08-4.53) |
eGFR: estimated glomerular filtration rate; NGAL: neutrophil gelatinase-associated lipocalin; KIM-1: kidney injury molecule-1; A1M: alpha-1-microglobulin; B2M: beta-2-microglobulin; RBP4: retinol-binding protein 4; OPN: osteopontin; MFI: mean fluorescence intensity; GSTα: glutathione S-transferase alpha.