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. Author manuscript; available in PMC: 2024 Dec 15.
Published in final edited form as: Environ Pollut. 2023 Oct 14;339:122756. doi: 10.1016/j.envpol.2023.122756

Figure 1.

Figure 1.

The involvement of multiple organ systems and interactions in PCB exposure induced toxicity (created with BioRender.com). AhR: aryl hydrocarbon receptor; FMO3: flavin-containing monooxygenase 3; HNF-1b: hepatocyte nuclear factor-1b; ICAM-1: intercellular cell adhesion molecule-1; LPS: lipopolysaccharide; MAPK: mitogen-activated protein kinase; NAFLD: nonalcoholic fatty liver disease; NF-κB: nuclear factor kappa-B; NLRP3: NOD-like receptor thermal protein domain associated protein 3; PAI-1: plasminogen activator inhibitor-1; PCB: polychlorinated biphenyl; ROS: reactive oxygen species; TMAO: trimethylamine oxide.