Table 1.
Baseline characteristics of women, age 40-74 years, with a history of AH or LCIS, undergoing screening mammography at Columbia University Irving Medical Center, New York, NY, stratified by Non-Hispanic White vs Racial/Ethnic Minority
| Characteristic | White (N=97, 32.6%) |
Non-White (N=201, 67.5%) |
Total (N=298) |
P-value |
|---|---|---|---|---|
| Mean age (SD) | 60.5 (8.4) | 57.1 (8.2) | 58.2 (8.3) | 0.001 |
| Mean systolic blood pressure (SD), mm Hg | 120.6 (16.3) | 127.8 (15.4) | 125.4 (16.0) | <.001 |
| Mean total cholesterol (SD), mg/dL | 202.7 (39.7) | 195.6 (43.4) | 197.9 (42.3) | 0.174 |
| Mean HDL cholesterol (SD), mg/dL | 69.7 (19.7) | 60.1 (17.2) | 63.2 (18.6) | <.001 |
| History of diabetes, N (%) | ||||
| Yes | 15 (15.5) | 71 (35.3) | 86 (28.9) | <.001 |
| No | 82 (84.5) | 130 (64.7) | 212 (71.1) | |
| Treatment for hypertension, N (%) | ||||
| Yes | 37 (38.1) | 107 (53.2) | 144 (48.3) | 0.015 |
| No | 60 (61.9) | 94 (46.8) | 154 (51.7) | |
| Current smoker, N (%) | ||||
| Yes | 2 (2.1) | 6 (3.0) | 8 (2.7) | 0.644 |
| No | 95 (97.9) | 195 (97.0) | 290 (97.3) | |
| High-risk for ASCVD, N (%) | ||||
| Yes | 33 (34.0) | 56 (24.9) | 89 (29.9) | 0.276 |
| No | 64 (66.0) | 145 (72.1) | 209 (70.1) | |
| Statin use, N (%) | ||||
| Yes | 29 (29.9) | 76 (37.8) | 105 (35.2) | 0.180 |
| No | 68 (70.1) | 125 (62.2) | 193 (64.8) | |
| Mean 10-year ASCVD risk, % (SD) | 6.3 (7.2) | 6.9 (8.4) | 6.7 (8.0) | 0.526 |
| First-degree relatives with breast cancer, N (%) | ||||
| Yes | 25 (25.8) | 40 (19.9) | 65 (21.8) | 0.469 |
| No | 70 (72.2) | 158 (78.6) | 228 (76.5) | |
| Unknown | 2 (2.1) | 3 (1.5) | 5 (1.7) | |
| Prior breast biopsy result, N (%) | ||||
| AH | 47 (48.5) | 145 (72.1) | 192 (64.4) | <.001 |
| LCIS | 50 (51.6) | 56 (27.9) | 106 (35.6) | |
| BI-RADS breast density, N (%) | ||||
| Almost entirely fatty | 2 (2.1) | 4 (2.0) | 6 (2.0) | 0.191 |
| Scattered fibroglandular densities | 32 (33.0) | 89 (44.3) | 121 (40.6) | |
| Heterogeneously dense | 60 (61.9) | 106 (52.7) | 166 (55.7) | |
| Extremely dense | 3 (3.1) | 2 (1.0) | 5 (1.7) | |
| High-risk for breast cancer, N (%) | ||||
| Yes | 97 (100.0) | 195 (97.0) | 292 (98.0) | 0.086 |
| No | 0 (0.0) | 6 (3.0) | 6 (2.0) | |
| Chemoprevention use, N (%) | ||||
| Yes | 23 (23.7) | 45 (22.4) | 68 (22.8) | 0.799 |
| No | 74 (76.3) | 156 (77.6) | 230 (77.2) | |
| Mean 10-year breast cancer risk, % (SD) | 12.1 (5.3) | 7.7 (3.2) | 9.1 (4.5) | <.001 |
- Abbreviations:
- ASCVD: Atherosclerotic Cardiovascular Disease
- AH: Atypical hyperplasia
- LCIS: Lobular carcinoma in situ
- BI-RADS: Breast Imaging and Reporting Data System
- Non-White includes Hispanic, non-Hispanic Black, Asian, and other/unknown race/ethnicity