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(A) Structures and (B) illustration of multistage chemical reactions in vitro. (C) Illustration of the site-specific construction of nanofibers in living cells through multistage processes for targeting lysosomes. (D) Cryo-EM images of 22 incubated with ACP at pH 5.0 for 24 h. Bar = 50 nm. (E) CLSM images of Saos-2 cells incubated with 22 (100 μM, 4h). Bar = 5 μm. Adapted from Ref.60 Copyright Wiley 2022
