FIG. 1.

IL-12 binding to LN cells from L. major-infected C3H and BALB/c mice. The results of a flow-cytometric analysis of IL-12 binding to lymphocytes isolated from the draining LNs of uninfected mice and mice infected 2 days previously are displayed. The data from one representative mouse from each group (n = 3 to 5) are shown. Peaks outlined by dark solid lines represent cells incubated with 0.5 μg of IL-12 and then stained with the anti-IL-12 MAb; these peaks are compared to those for control samples stained with the anti-IL-12 MAb alone (shaded peaks). These results are representative of four experiments.