Table III –
Summary of Studies Linking Ets1 to Human Autoimmune and Inflammatory Diseases
| Study | Disease | Type of Analysis | Population(s) |
|---|---|---|---|
| (Sullivan et al., 2000) | Systemic Lupus Erythematosus | Candidate gene approach | U.S. population |
| (Konno et al., 2004) | Inflammatory Bowel Disease | Candidate gene approach | Japanese population |
| (Hughes, 2005) | Crohn’s Disease | Microarray for RNA expression | European population |
| (Du et al., 2009) | Multiple Sclerosis | Target of miRNA | Chinese population |
| (Han et al., 2009) | Systemic Lupus Erythematosus | GWAS | Chinese population |
| (Dubois et al., 2010) | Celiac Disease | GWAS | European population |
| (He et al., 2010) | Systemic Lupus Erythematosus | Candidate gene approach | Chinese population |
| (Y. Li et al., 2010) | Systemic Lupus Erythematosus | Candidate gene approach | Chinese population |
| (Yang et al., 2010) | Systemic Lupus Erythematosus | GWAS | Chinese and Thai populations |
| (Trynka et al., 2011) | Celiac Disease | GWAS | European and Indian populations |
| (Zhong et al., 2011) | Systemic Lupus Erythematosus | Candidate gene approach | Chinese population |
| (Freudenberg et al., 2011) | Rheumatoid Arthritis | GWAS | Korean population |
| (Leng et al., 2012) | Systemic Lupus Erythematosus | Candidate gene approach | Chinese population |
| (Okada et al., 2012) | Rheumatoid arthritis | Meta-analysis of multiple GWAS | Japanese population |
| (Tsoi et al., 2012) | Psoriasis | Meta-analysis of multiple GWAS | U.S. and European populations |
| (Chatzikyriakidou et al., 2013) | Rheumatoid Arthritis | Candidate gene approach | European population |
| (Wang et al., 2013) | Systemic Lupus Erythematosus | Candidate gene approach | U.S. and European populations |
| (Wen et al., 2013) | Systemic Lupus Erythematosus | Target of miRNA | Chinese population |
| (Hinds et al., 2013) | Atopic Dermatitis | GWAS | U.S. and UK populations |
| (Zhang et al., 2013) | Systemic Lupus Erythematosus | Candidate gene approach | Chinese population |
| (Molineros et al., 2014) | Systemic Lupus Erythematosus | GWAS | Malaysian population |
| (Okada et al., 2014) | Rheumatoid Arthritis | Meta-analysis of multiple GWAS | European and Asian populations |
| (Shan et al., 2014) | Ankylosing Spondylitis | Candidate gene approach | Chinese population |
| (Wei et al., 2014) | Pediatric Uveitis | Candidate gene approach | Chinese population |
| (Zhang et al., 2014) | Rheumatoid Arthritis | Candidate gene approach | Chinese population |
| (Bentham et al., 2015) | Systemic Lupus Erythematosus | GWAS | European and US populations |
| (Chen et al., 2015) | Rheumatoid Arthritis | Candidate gene approach | Chinese population |
| (Kim et al., 2015) | Rheumatoid Arthritis | GWAS | Korean population |
| (Lill et al., 2015) | Multiple Sclerosis | Candidate gene approach | European population |
| (Lu et al., 2015) | Systemic Lupus Erythematosus | Candidate gene approach | United States, Asian, and European populations |
| (Paternoster et al., 2015) | Atopic Dermatitis | Meta-analysis of multiple GWAS | European, African, Japanese and Latino populations |
| (Yin et al., 2015) | Psoriasis | Meta-analysis of multiple GWAS | Chinese and Caucasian populations |
| (Lessard et al., 2016) | Systemic Lupus Erythematosus | GWAS | Korean population |
| (Mansouri et al., 2016) | Systemic Lupus Erythematosus | Candidate gene approach | Iranian population |
| (Morris et al., 2016) | Systemic Lupus Erythematosus | GWAS | Chinese and European populations |
| (Na et al., 2016) | Behçet’s disease | Target of miRNA | Korean population |
| (Sun et al., 2016) | Systemic Lupus Erythematosus | Target of miRNA | Chinese population |
| (Vedak et al., 2016) | TNF-α Antagonist Associated Psoriasis in Inflammatory Bowel Diseases | GWAS | U.S. population |
| (Chen et al., 2017) | Idiopathic Inflammatory Myopathies | Candidate gene approach | Chinese population |
| (Danila et al., 2017) | Rheumatoid Arthritis | GWAS | U.S. population |
| (Boyd et al., 2018) | Inflammatory Bowel Disease | In silico predictions | N/A |
| (Jenks et al., 2018) | Systemic Lupus Erythematosus | RNA-seq | U.S. population |
| (Kawasaki et al., 2018) | Granulomatosis with Polyangiitis | Candidate gene approach | Japanese population |
| (Kim et al., 2018) | Systemic Lupus Erythematosus | Candidate gene approach | Korean population |
| (Weeding et al., 2018) | Anti-phospholipid Syndrome | CpG Methylation Assay | U.S. population |
| (Ge et al., 2019) | Inflammatory Bowel Disease | Target of miRNA | Chinese population |
| (Jin et al., 2019) | Systemic Lupus Erythematosus | Target of miRNA | Chinese population |
| (Jones et al., 2019) | Systemic Lupus Erythematosus | In silico predictions | N/A |
| (Laufer et al., 2019) | Rheumatoid Arthritis | Meta-analysis of multiple GWAS | Multiple populations |
| (Xu et al., 2019) | Primary Biliary Cholangitis | Candidate gene approach | Chinese population |
| (Zhang et al., 2019) | Systemic Lupus Erythematosus | Candidate gene approach | Chinese population |
| (Li et al., 2020) | Multiple Sclerosis | Target of miRNA | Chinese |
| (Akhtar et al., 2021) | Systemic Lupus Erythematosus | In silico predictions | N/A |
| (Sobczyk et al., 2021) | Atopic Dermatitis | In silico predictions | N/A |
| (Tanaka et al., 2021) | Atopic Dermatitis | GWAS | Japanese population |
| (Wang et al., 2021) | Asthma | Microarray for RNA expression | Chinese population |
| (Yang et al., 2021) | Rheumatoid Arthritis | Candidate gene approach | Chinese population |
| (Cooles et al., 2022) | Rheumatoid Arthritis | In silico predictions | European population |
| (He et al., 2022) | Inflammatory Bowel Disease | Candidate gene approach | Chinese population |
| (Suzuki et al., 2022) | Systemic Lupus Erythematosus | Candidate gene approach | Japanese population |