Table 1.
Demographics and clinical data of glioblastoma patients.
| Patient characteristics | |||
|---|---|---|---|
|
| |||
| High p-ERK (n=12) | Low p-ERK (n=12) | Total number of patients (n=24) | |
|
| |||
| Cohort (%) | |||
| Cohort 1 (nivo) | 2 (16.67) | 1 (8.33) | 3 (12.5) |
| Cohort 2 (nivo + ipi) | 10 (83.33) | 11 (91.67) | 21 (87.5) |
| Age | |||
| Mean ± s.d. | 59.2 (10.5) | 51.8 (10.1) | 55.5 (10.8) |
| Median (Range) | 62.2 (41.5–72.4) | 53.4 (37.7–70.3) | 55.1 (37.7–72.4) |
| ECOG PS (%) | |||
| 0 | 3 (25) | 7 (58.33) | 10 (41.67) |
| 1 | 7 (58.33) | 5 (41.67) | 12 (50) |
| 2 | 2 (16.67) | 0 | 2 (8.33) |
| IDH status, n (%) | |||
| Wild type | 11 (91.67) | 11 (91.67) | 22 (91.67) |
| Mutant | 1 (8.33) | 1 (8.33) | 2 (8.33) |
| Use of corticosteroids (%) | |||
| No | 10 (83.33) | 6 (50) | 16 (66.67) |
| Yes | 2 (16.67) | 6 (50) | 8 (33.33) |
s.d: standard deviation
High p-ERK: > 540.5 cells/mm2 Low p-ERK: <= 540.5 cells/mm2