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. Author manuscript; available in PMC: 2024 Jul 4.
Published in final edited form as: Cancer Prev Res (Phila). 2024 Jan 4;17(1):29–38. doi: 10.1158/1940-6207.CAPR-23-0091

Figure 2. Differentially abundant species in early- and late-onset CRC vs. Control.

Figure 2.

A volcano plot showing differentially abundant species (red dots) in early-onset CRC vs. control subjects of respective age group of <50 years (A) and a bar plot showing the coefficient change of significant taxa of species-level using a multivariable linear model by disease status adjusting for country, BMI, gender, DNA extraction methods of early-onset CRC (B). A volcano plot showing differentially abundant species (red dots) in late-onset CRC vs. subjects of respective age group of >65 years (C). A bar plot showing the coefficient change of significant taxa of species-level using a multivariable linear model by disease status adjusting for country, BMI, gender, DNA extraction methods of late-onset CRC vs. control subjects (D). The criteria for significance included a p-value < 0.05, a q-value to control the False-Discovery Rate of < 0.25, and a log2 Fold Change of +/− 1.25.