Skip to main content
. Author manuscript; available in PMC: 2024 Dec 15.
Published in final edited form as: Neuropharmacology. 2023 Sep 30;241:109738. doi: 10.1016/j.neuropharm.2023.109738

Figure 1. Ethanol (EtOH) exposure at postnatal day 7 activated apoptotic pathways in anterior thalamic neurons.

Figure 1.

Images from VGAT-Venus mice from the Air (control) (A) and 8 hours post EtOH vapor conditions (B). Red: cleaved caspase 3 (CC3), blue: DAPI, green: Venus. AD, anterodorsal thalamic nucleus; AV, anteroventral thalamic nucleus; TRN, thalamic reticular nucleus. C) Panoramic image illustrating the AD, AV, and TRN location in a coronal brain slice of a P7 VGAT-Venus mouse. Blue: DAPI; green: Venus. D). Summary data of the effect of EtOH treatment on the percentage of DAPI-positive cells that were positive for cleaved caspase 3 (CC3) in the AD nucleus (p<0.0001), AV nucleus (p<0.0001) and TRN (p=0.032) (Šídák’s multiple comparisons test for control vs. EtOH). Control, n=4 pups (2 males and 2 females from 2 litters) and EtOH, n=5 pups (4 males and 1 female from 3 litters).