Table 1.
Baseline participant characteristics of the Chronic Kidney Disease in Children and the Neurocognitive Assessment and Magnetic Resonance Imaging Analysis of Children and Young Adults with Chronic Kidney Disease studies
| Participant Characteristics | CKiD | NiCK | ||
|---|---|---|---|---|
| Overall | Subset with Follow-Up | CKD | Controls | |
| No. | 569 | 360 | 60 | 67 |
| Age, yr, median (IQR) | 12 (8–15) | 11 (8–14) | 16 (14–18) | 16 (13–18) |
| Sex, male, n (%) | 344 (60) | 220 (61) | 36 (60) | 37 (54) |
| Non-Hispanic Black race, n (%) | 111 (19) | 62 (17) | 18 (30) | 26 (38) |
| Hispanic ethnicity, n (%) | 74 (13) | 43 (12) | 3 (5) | 0 (0) |
| Abnormal delivery history, n (%) | 115 (20) | 67 (19) | 20 (33) | 20 (29) |
| eGFR, median (IQR) | 53 (40–67) | 52 (39–66) | 55 (29–73) | — |
| UPCR, median (IQR) | 0.3 (0.1–0.9) | 0.3 (0.1–0.7) | 0.7 (0.2–1.6) | — |
| CKD duration, yr, median (IQR) | 9 (4–13) | 8 (5–12) | 9 (3–15) | — |
| Glomerular diagnosis | 169 (30) | 93 (26) | 19 (32) | — |
| Hypertension | 404 (71) | 242 (67) | 31 (52) | — |
There were 569 CKiD participants with any complete neurocognitive assessment at baseline. A subset of 360 had longitudinal follow-up. NiCK participants were older than CKiD participants at baseline. NiCK participants had a larger percentage representation of non-Hispanic Black race. CKiD, Chronic Kidney Disease in Children; NiCK, Neurocognitive Assessment and Magnetic Resonance Imaging Analysis of Children and Young Adults with Chronic Kidney Disease; IQR, interquartile range; UPCR, urine protein/creatinine ratio.