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. 2005 Apr 22;33(7):2310–2317. doi: 10.1093/nar/gki526

Table 1.

Potential targets of radicicol (containing the ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase: http://supfam.mrc-lmb.cam.ac.uk/SUPERFAMILY/index.html)

Halobacteria Sulfolobales E.coli Eukaryotes
Gyrase/Topo IV + +(2) + (plants)
Topo II +
Topo VI + + + (plants)
Histidines kinases +(13) +(29) +
Hsp90 family + +
MutL family + + +