Figure 3. Close-Up View of the GUN4 Core Domain's “Cupped Hand” Architecture.

(A) Rendered skeletal view of the GUN4 core domain. Helices are shown as red cylinders, and coiled regions are depicted as gray loops. The overall shape resembles that of a “cupped hand.”

(B) Rendered view of the solvent-accessible surface of the GUN4 core domain, colored gold. The α6/α7 loop is colored gray and is bound by the remainder of the domain. The “cupped hand” grips this loop.