Table 1.
Percentage of cells with indicated expression pattern1 | |||||
Age | Genotype | Sca-1+/CD45- | Sca-1+/CD45+ | Sca-1-/CD45+ | Sca-1-/CD45- |
3 weeks | C57BL/6 | 5.9 ± 3.5 | 1.0 ± 0.4 | 4.7 ± 1.7 | 88.0 ± 5.3 |
Lama2-/- | 5.6 ± 1.8 | 3.3 ± 0.4 | 38.9 ± 15.9 | 52.2 ± 15.6 | |
P > 0.1 | P < 0.03* | P < 0.01* | P < 0.01* | ||
4 weeks | C57BL/10 | 12.0 ± 6.7 | 1.2 ± 0.2 | 8.3 ± 2.2 | 78.6 ± 4.3 |
mdx | 21.0 ± 7.4 | 6.4 ± 2.4 | 55.8 ± 11.3 | 16.7 ± 6.2 | |
P > 0.1 | P = 0.09 | P < 0.03* | P < 0.01* | ||
7.5 weeks | C57BL/10 | 2.5 ± 0.6 | 0.2 ± 0.1 | 5.1 ± 0.2 | 92.0 ± 0.6 |
mdx | 1.8 ± 0.5 | 0.8 ± 0.3 | 28.9 ± 3.6 | 68.5 ± 4.1 | |
P > 0.1 | P = 0.03* | P < 0.01* | P < 0.01* |
1Data are presented as ave. ± SD with n = 3 for all except 4 week old values where n = 2.
Unpaired, two-tailed t-tests (see Methods) were used to compare values from each pair of healthy and diseased muscles that were of the same age and expression pattern. P values are shown below the pair of tested values. P ≤ 0.05 was considered significant and indicated by an asterisk.