Table 4.

Thiamine diphosphate utilizing enzymes. Enzymes are arranged by their sequential functional order. They are given by their name, their EC numbers, the gene identification (PfID) in the Plasmodium genome database (PlasmoDB), the time (in hours post invasion (HPI)) in the parasite's developmental cycle when they are maximally transcribed obtained from the IDC database, the metabolic function of the enzyme.

Enzyme	EC number	PfID	HPI	Metabolic function
Pyruvate dehydrogenase E1	1.2.4.1	PF11_0256 (a) PF14_0441 (b)	28 28	Apicoplast fatty acid synthesis
Transketolase	2.2.1.1	MAL6P1.110	17	Pentose phosphate pathway
Oxalyl-CoA decarboxylase	4.1.18	MAL6P1.231 PFF0945c	26 NA	Glyoxylate and dicarboxylate metabolism
1-deoxy-D-xylulose-5-phosphate synthase	2.2.1.7	PF13_0207	21	Isoprenoid biosynthesis
3-methyl-2-oxobutanoate dehydrogenase	1.2.4.4	PFE0225w	32	Leucine, isoleucine and valine degradation
Oxoglutarate dehydrogenase	1.2.4.2	PF08_0045	32	Mitochondrial TCA cycle