Table 2.
Characteristics | Univariate HRsd (95% CI) | P-value | Multivariate aHRsd (95% CI) | P-value |
---|---|---|---|---|
| ||||
Country | <0.001 | <0.001 | ||
Uganda | 1 | 1 | ||
Botswana | 1.44 (1.36 – 1.52) | 2.00 (1.91 – 2.10) | ||
Sex | ||||
Female | 1 | <0.001 | ||
Male | 1.19 (1.14 – 1.24) | |||
Age at Enrollment (per 1-year increase) | 0.20 (0.18 – 0.22) | 0.011 | 0.18 (0.16 – 0.20) | 0.001 |
Year Birth | ||||
Before 2004 | 1 | <0.001 | ||
After 2004 | 3.45 (3.22 – 3.70) | |||
Year of enrollment | <0.001 | |||
Before 2006 | 1 | 1 | ||
2006–2009 | 0.96 (0.91 – 1.01) | 0.14 | 1.14 (1.07 – 1.22) | |
After 2010 | 1.19 (1.12 – 1.26) | <0.001 | 1.13 (1.02 – 1.24) | |
HIV RNA load, (log10 copies/μl)a | 1.89 (1.52 – 2.30) | <0.001 | ||
Weight-for-age Z-score (per Z increase) | 0.68 (0.64 – 0.72) | 0.031 | 0.77 (0.68 – 0.87) | <0.001 |
−1.75 | 1 | 1 | ||
−3.75 | 1.24 (1.16 – 1.34) | 1.42 (1.32 – 1.53) | ||
Height-for-age z-score (per Z increase) | 0.86 (0.83 – 0.88) | <0.001 | 1.00 (0.92 – 1.08) | 0.91 |
−1.75 | 1 | 1 | ||
−3.75 | 1.22 (1.17 – 1.27) | 1.03 (0.96–1.09) | ||
BMI-for-age z-score (per Z increase)b | 0.79 (0.76 – 0.82) | <0.001 | ||
−0.85 | 1 | |||
−2.85 | 1.32 (1.28 – 1.38) |
Abbreviations: aHRsd, adjusted subdistribution hazard ratio; BMI, body mass index; CI, confidence interval.
N = 10078
n = 847
BMI-for-age was not included in any model with weight-for-age or height-for-age.