Table 2.
Temporal changes of significantly up-regulated genes in aposymbiotic animals relative to symbiotic animals under gravity and low-sheared modeled microgravity (LSMMG) conditions with adjusted p-value ≤ 0.10a.
| 2h | 6 h | 8 h | 10 h | 12 h | 16 h | 18 h | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Treatment | APO | SYM | APO | SYM | APO | SYM | APO | SYM | APO | SYM | APO | SYM | APO | SYM |
| Gravity | n/a | n/a | TRAF4 | EsPGRP2 | MYD88 | EsPGRP2 | MYD88 | EsPGRP2 | IRAK4 | EsPGRP2 | HSP71 | EsPGRP2 | n/ab | EsPGRP2 |
| MYD88 | IκBα | HSP90 | TBK1 | HSP90 | TBK1 | LysM3 | TBK1 | TBK1 | TBK1 | |||||
| IκBα | HSP71 | IκBα | IKKε | IκBα | IκBζ | IκBζ | ||||||||
| EsIKKγ | EsPGRP5 | IκBζ | IKKβ | IκBα | IκBα | |||||||||
| IKBL | EsGalectin1 | EsIKKγ | EsPGRP3 | IRAK4 | ||||||||||
| TRAF3 | EsTRAF6 | EsIKKγ | ||||||||||||
| LysM3 | EsIKKγ | EsTRAF6 | ||||||||||||
| IKBL | TRAF3 | |||||||||||||
| TRAF2 | ||||||||||||||
| LSMMG | EsPGRP3 | IκBα | IKBL | EsPGRP2 | IKBL | EsPGRP2 | EsTRAF6 | EsPGRP2 | EsPGRP5 | EsPGRP2 | n/a | EsPGRP2 | n/a | EsPGRP2 |
| EsGalectin1 | TRAF2 | TRAF2 | TBK1 | TLR3 | IκBα | HSP90 | TBK1 | HSP90 | TBK1 | IκBζ | TBK1 | |||
| HSP90c | LysM3 | LysM3 | IκBα | TLR4 | TBK1 | MYD88 | IκBα | HSP71 | IκBα | EsPGRP3 | IκBζ | |||
| IRAK4 | IKBL | TAB3 | HSP90 | TAK1 | IκBζ | EsPGRP3 | EsSOD | IκBζ | IRAK4 | EsPGRP3 | ||||
| HSP71 | TRAF4 | EsSOD | TRAF4 | IκBζ | EsTRAF6 | TBK1 | IκBα | |||||||
| EsSOD | IKKε | EsIKKγ | TRAF3 | EsIKKγ | EsTRAF6 | |||||||||
| TRAF3 | TRAF2 | TOLIP | IRAK4 | |||||||||||
| EsIKKγ | ||||||||||||||
| TRAF3 | ||||||||||||||
| TOLIP | ||||||||||||||
aFold changes and adjusted p-values listed in Dataset S2.
bIndicates no significantly differentially expressed genes at this time point.
cGenes in italics exhibit earlier temporal expression under LSMMG, whereas expression of genes in bold were delayed under LSMMG conditions relative to gravity controls.