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. 2023 Dec 21;130(3):467–475. doi: 10.1038/s41416-023-02542-1

Table 2.

Dose Limiting Toxicities observed in cohort A1 and A2.

A1 A2
Schedule N Number of patients with DLTs Posterior estimates of toxicity (95% Cred. Interval) N Number of patients with DLTs Posterior estimates of toxicity (95% Cred. Interval)
1 3 0 0.008 (0.000, 0.064) 4 0 0.091 (0.009, 0.256)
2 1 0 0.012 (0.000, 0.085) 1 0 0.111 (0.014, 0.291)
3 1 0 0.016 (0.000, 0.108) 9 2 0.146 (0.026, 0.345)
4 1 0 0.019 (0.000, 0.124) 4 0 0.185 (0.042, 0.397)
5 1 0 0.023 (0.000, 0.140)
6 9 0 0.029 (0.000, 0.165)