Table 3.

a: Five most common system organ classes to experience adverse events by grade in A1. b: Five most common system organ classes to experience adverse events by grade in A2.

	One (n = 66)	Two (n = 19)	Three (n = 16)	Four (n = 0)	Total (n = 101)
a
System Organ Class – A1
Gastrointestinal Disorders	20 (30.3)	6 (31.6)	2 (12.5)	0 (NaN)	28 (27.7)
Skin and subcutaneous tissue disorders	8 (12.1)	2 (10.5)	4 (25.0)	0 (NaN)	14 (13.9)
Respiratory, thoracic and mediastinal disorders	11 (16.7)	0 (0.0)	0 (0.0)	0 (NaN)	11 (10.9)
General Disorders & Administration Site Conditions	6 (9.1)	2 (10.5)	2 (12.5)	0 (NaN)	10 (9.9)
Investigations	4 (6.1)	0 (0.0)	3 (18.8)	0 (NaN)	7 (6.9)

	One (n = 159)	Two (n = 54)	Three (n = 26)	Four (n = 3)	Total (n = 242)
b
System Organ Class – A2
General Disorders & Administration Site Conditions	27 (17.0)	16 (29.6)	0 (0.0)	0 (0.0)	43 (17.8)
Gastrointestinal Disorders	33 (20.8)	5 (9.3)	1 (3.8)	0 (0.0)	39 (16.1)
Blood & Lymphatic System Disorders	12 (7.5)	9 (16.7)	13 (50.0)	3 (100.0)	37 (15.3)
Investigations	18 (11.3)	6 (11.1)	1 (3.8)	0 (0.0)	25 (10.3)
Infections & Infestations	14 (8.8)	5 (9.3)	1 (3.8)	0 (0.0)	20 (8.3)